A pacemaker is a small, electrically charged device which is implanted under the skin to help manage arrhythmias or irregular heartbeats. A pacemaker is required if a person’s heart is beating too slow or too fast. In any case, the body does not get adequate blood supply. This can result in shortness of breath, fatigue, damage to vital organs, lightheadedness or fainting, and eventual death. A pacemaker controls the electrical system of the heart that manages heart rhythms.
The global pacemaker market is anticipated to grow at a CAGR of over 9.2 % from 2014 to 2025, as per a new report published by Grand View Research Inc. This growth is attributed to the factors such as growing prevalence of cardiovascular conditions (heart diseases) and the availability of medical coverage.
Medtronic PLC recently launched the world’s smallest pacemaker called Micra Transcatheter Pacing System (TPS). This device provides the highly developed pacing technology and is as big as a large vitamin capsule! The Micra TPS was intended especially for patients who need more than one heart devices. The device has an exclusive feature that allows it to be permanently turned off. This enables the device to remain in the body while a new device can be implanted without any risks of electrical interaction. Approved by the United States Food & Drug Administration (FDA), TPS is the only leadless device accepted for use.
This device can be carried using a catheter and implanted into the heart, providing a safer replacement to the usual pacemakers without any of the leads-related complexities. The major advantage of the device is that it lets automatically set pacing therapy and has a battery that can last for approximately 10 years.
The global pacemaker market is said to reach USD 12.3 billion by 2025. The major factors driving the market growth are growing occurrences of Cardiovascular Diseases (CVDs) and rising awareness levels regarding CVDs and their long-term effects. This is also increasing the popularity of advanced treatment options, which is likely to increase the usage rates of the product. The key companies operating in the global pacemaker market are ZOLL Medical Corp.; MEDICO S.p.A.; Medtronic PLC; Cordis Inc.; and Boston Scientific Corp.
Intracranial pressure (ICP) monitoring devices market is expected to witness substantial growth over the forecast period (from 2014 to 2025)
Intracranial pressure measurements are important in the treatment and evaluation of neurological diseases such as intracerebral (ICH) hemorrhage, subarachnoid hemorrhage (SAH), hydrocephalus, traumatic brain injury (TBI), encephalitis/meningitis, and ischemic stroke. The global intracranial pressure (ICP) monitoring devices market is expected at USD 1.9 billion by 2025, according to a report by Grand View Research, Inc. This growth can be attributed to the rising neurological ailments and awareness about the treatments available for these ailments. In addition, extensive research funding and high disease occurrences together are likely to impact the market growth positively. However, the high price associated with the advanced ICP monitoring devices along with the lack of expert professionals in the upcoming regions is one of the major factors that may hamper the growth of the global industry.
There are a number of products available to efficiently carrying out the operations of the ICP monitoring device such as Integra Neuroscience Products. The Integra Neuroscience external drainage catheter is a Cerebrospinal Fluid (CSF) diversion system. This device is instrumental in evaluating the ICP. It has transparent catheter tubing with depth markings and includes a strip of radio-opaque barium sulfite. Intracranial pressure readings are based on a transduction system that is fluid-filled and puts out the ICP changes through a tube (saline-filled) to a diaphragm placed on strain gauge transducer. After insertion, this monitoring device has to be leveled with Foreman of Monro (the External Auditory Canal’s (EAC) level) and must be zero-balanced every day. The level of the drain is adjustable in order to allow less or more CSF drainage.
The global intracranial pressure (ICP) monitoring devices market is expected to witness substantial growth over the forecast period (from 2014 to 2025). The growing number of patients suffering from severe neurological disorders that can cause high intracranial pressure is said to drive the growth of the global industry over the next few years. The major intracranial pressure monitoring devices manufacturers are Codman & Shurtleff, Inc.; RAUMEDIC AG.; and Integra LifeSciences Holdings Corp. All these key companies are present globally and—due to trouble-free accessibility to the international market—are now competing with each other in order to achieve greater industry share.
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Global Fuel Injection Systems Market has received a tremendous boost in recent years on account of rising environmental concerns and regulations regarding carbon emissions. On account of increasing population, improved lifestyles and subsequent demand for passenger cars, fuel injection systems are expected to grow at a rapidly increasing rate. Fuel injection systems are vital components in any automotive engine that regulate and monitor the amount of fuel entering the engine cylinders as per requirements. Modern fuel injection systems not only regulate the flow of fuel, but also provide additional functions such as multiple, pilot, post injections and rate shaping (scheduling), which is expected to contribute largely to the growth of the market. Several factors such as reliability, ability to accommodate alternative fuels, increased efficiency and output are also anticipated to be imperative factors for fuel injection systems demand. Fuel injected engines are also much easier to start up, requiring no choke and also contribute to savings over fuel, which may foster the growth of global market. Development of diesel fuel injection systems has propelled the demand for diesel passenger cars across the globe. Alternative developments supporting fuel injection systems in 150cc engines and below has allowed exploration of untapped two-wheelers market. Further advancements in fuel injection systems are also expected to boost the market growth.
Certain drawbacks such as high maintenance costs and increased service complexity are expected to hamper the global fuel injection systems market growth. Increased un-burnt hydrocarbons may also lead to higher emission rates which are anticipated to negatively impact fuel injection systems market over the forecast period.
Fuel injection systems market on basis of vehicle types include passenger, commercial, heavy trucks, buses and two-wheelers. Highest growth has been witnessed in the passenger car segment on account of rising per capita income and demand for personal transportation. Classification on the basis of engine types includes gasoline and diesel, with global preference towards gasoline technology on account of fuel efficiency and environmental concerns. Various technologies of fuel injection systems include port injection, diesel direct injection and gasoline direct injection. Further classification on the basis of components includes high pressure pumps, pressure regulators, ECU and injectors.
The global medical laser systems market is expected to reach USD 12.5 billion by 2022, according to a new report by Grand View Research, Inc. Rising demand for minimal and non-invasive procedures by patients is anticipated to be the most impact rendering driver of the market.
Increasing application of these systems for diagnostic purposes, rising geriatric population base, propelling demand for cosmetic surgeries and technological advances in pre-existing laser systems are vital factors driving the demand of this market.
Medical laser systems are being prominently applied in various branches of biology such as urology, cardiology, ophthalmology etc for the purpose of diagnosis, disease management and prevention. Augmenting cases of these disorders is expected to positively impact market growth over the forecast period.
Solid state lasers are anticipated to grow at the fastest rate during the forecast period due to higher reliability, smaller compact designs, lowered cost of purchase and prolonged life span of the systems. Diode lasers are expected to hold a significant market share owing to the introduction of next generation Optically Pumped Semiconductor Lasers (OPSLs) that provide unmatched electrical efficiency.
North America medical laser systems market, by product, 2012-2022, (USD Million)
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Further key findings from the report suggest:
- Solid state lasers are expected to grow at the fastest rate of over 10% during the forecast period due to technological advances and increasing application in diagnostic field. Neodynium Yttrium Aluminum Garnet (Nd:Yag) and Potassium titanyl phosphate (KTP) are expected to drive growth over the forecast period.
- On the basis of application segments, urology, cardiology and gynecology are expected to be the top contributors of the medical laser systems market. Statistics provided by the WHO estimate that over 17.5 million people annually are reported with chronic cases of cardiovascular disorder that require surgical follow-up.
- North America held over 35.0% of the market in 2014 due to rising disposable income, rising geriatric population base coupled with increasing cases of age-related disorders and conditions.
- Asia Pacific is anticipated to witness lucrative growth and capture over 25.0% share of the global market by 2022. Rising disposal income, increasing awareness and volume of cosmetic surgeries, increasing incidences of diabetic retinopathy, rheumatoid arthritis and dental caries are key drivers for the medical laser systems market growth within the region.
- Eminent players of this market include IRIDEX Corp., Lumenis Ltd., Syneron-Candela, Photomedex Inc., Spectranetics Corp., Biolase Inc., Bioform Medica Inc., biolitec, and Cutera.
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Global tissue engineering market is expected to reach USD 11.53 billion by 2022, according to a new report by Grand View Research, Inc. The demand for tissue engineering is expected to upsurge owing to the shift of focus from stem cell therapies to immunocelluar therapies. Moreover, companies such as Caladrius and Celyad changed their names from Cardio3 Bio NeoStem respectively to reflect their focus on immunotherapies.
The market is also experiencing industry-academia collaboration to make the commercialization of viable cell therapies possible. In July 2015, Fate Therapeutics, Inc. collaborated with theUniversity of Minnesota to research on Natural Killer (NK) therapeutics, which can detectand kill the malignant cells. The research is expected to accelerate with the use of programmed therapeutics by Fate Therapeutics.
With the technological advancements, researchers are working upon custom-made body parts with the aid of biomaterials and bio 3D printing. The demand for orthopedic implants is continuously growing; however, there is a gap between the demand and supply. To address such issues, researchers are experimenting with ways to find out alternatives, which use in-vitro testing and humane substitutes.
Investigators are working on ways to develop 3D printed organs, which can offer low-cost implantation. This step can revolutionize the 3D printing industry, but many hurdles such as donor availability, technologically-advanced 3D printers, and financial barriers have to be overcome. For instance, the cost of 3D printing ranges from USD 100 for tracheal split to USD 40,000 for nose bio-printing. Thus, there is a need for scientists and researchers to work on this multidisciplinary aspect of bio-printing.
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Orthopedics dominated the application segment in 2014 owing to the continuous launch of new products and research funding. In February 2016, Geistlich Pharma launched a range of bone harvesting instrument for the efficient collection of autogenous bone. Implant of only autogenous bone causes resorption and volume depletion. With the use of Geistlich Bio-Oss-pioneered technology, the volume as well as properties of bone is restored.
North America was the largest regional market with a revenue share estimated at over 50% owing to the various mergers and acquisitions along with huge funds available for research. In March 2016, Zimmer Bimet acquired Ortho Transmission for its pioneered technology, which could restore limb amputee patients.
By acquiring the skeletal implant technology, Zimmer can efficiently work on its current project received by the U.S. Department of Defense to develop external prosthetic limbs. Moreover, in February 2016, Canadian scientists from the University of Toronto’s dentistry pioneered a 3D printed method for absorbable bone-implant.
Europe was the second largest market in 2014, due to the amount of research and the funding received by the research universities. For instance, in June 2014, the European Union funded the VascuBone project to offer an alternative to bone grafts. The University Hospital of Wurzburg developed a toolbox to bring together the solutions required to offer ideal therapy to patients.
Countries in Europe are also expanding their research knowledge by partnering with other countries’ research firms. For instance, in March 2013, Johannes Gutenberg University Mainz and Chinese Academy of Sciences formed the Chinese-German Joint Center for Bio-Inspired Materials. The scientists will work on using marine animals for osteoporosis medication.
Asia Pacific is the fastest growing regional segment on the account of increasing interest of foreign players to establish their facilities in economically developed countries such as India and Japan. In August 2013, the Japan Health Ministry approved the clinical trial of the developing induced pluriponent stem (iPS) cells for blindness. The cells are morphed into retinal cells and then given to six patients with macular degeneration (AMD).
India is in an ascent stage of research and trying to develop in the tissue engineering area. In February 2016, India Biotechnology Event was held, where experts blamed the snail pace of development to the tedious and long approval process. The suggestion was to adopt Japan’s new executed law, where the sponsor has to demonstrate only the safety and efficacy studies of the device.
Key players of this market includeMedtronic, Inc., Zimmer Biomet, Acelity, Acell, Inc., Athersys, Inc., Organogenesis, Inc., Stryker Corporation, Tissue Regenix Group Plc, RTI surgical, Inc., and ReproCell, Inc.
Industry contributors are establishing their market presence by acquiring other companies or by launching new products in the market. In November 2015, ReproCell, Inc. acquired Biopta to leverage on Bipota’s clinical network in the U.S and the UK. Biopta has worked on around 500 new medicines and has partnerships with Scottish Enterprise and the NHS. Moreover, in February 2016, RTI Surgical, Inc. received exclusive licensing rights by RTI Surgical, Inc. Through this, RTI can access the OPM’s OsteoFab technology for spinal procedures.
Rising geriatric population and prevalence of respiratory diseases owing to increasing air pollution and unhealthy dilatory habits are some of the key factors driving the demand for medical gases and equipment. On the other hand, the global scarcity of helium is impeding the growth of the market.
Implementation of favorable regulations by governments worldwide is augmenting the growth of the market. The Food and Drug Administration Safety and Innovation Act (FDASIA) is one of the examples of such regulatory guidelines supporting the market growth. FDASIA enables withdrawal of drug user fees, approval of medical gasses for clinical usage, and also offer favorable intellectual protection right for innovative products.
Oxygen gas dominated the global medical gases market with a share of more than 44% in 2013. Rising number of patients suffering from respiratory diseases has been primarily boosting the growth of the oxygen gas among other segments.
Nitrous oxide accounted for around 25% of global market in 2013. The market share of the segment is expected to shrink during the forecast period since Increasing replacement of the gas by anesthetic drugs is expected to result in slow growth of nitrous oxide over the forecast period.
Medical pure gas dominated the market with a revenue of USD 1.7 billion in 2013. Rising prevalence of various respiratory disorders in geriatric population was the key driving factor for the growth of medical pure gases market.
Medical gases mixtures are anticipated to grow at a CAGR of 11.1% from 2014 to 2020. Increasing demand for the product in various medical administrations such as bypass surgery, renal dialysis, sterilization and other particular conditions are some of the factors responsible for the growth of the segment.
Vacuum systems dominated the overall equipment segment market share of more than 30% in 2013. Extensive research and development followed by constant innovation in the products are anticipated to widen its application in the respiratory disease treatment during the forecast period.
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Medical masks are fastest growing medical equipment and is expected to show CAGR of around 9% from 2014 to 2020. Largest revenue share of the segment was majorly attributed to low production costs coupled with very high usage rates. Manifolds, regulators, and outlet are some of the segments that are also expected to witness significant gains in near future.
North America contributed to more than 40% of the overall revenue share and was worth USD 2.48 billion in 2013. The presence of anadvanced healthcare infrastructure, the high adoption rate for advanced technologies and reimbursement coverage are some of the factors resulting in the dominance of the region. Europe was the second largest regional market after North America with a market share of around 19% in 2013.
Asia Pacific is anticipated to be the fastest growing market with CAGR of 9.9% during the forecast period. High air pollution index resulting in a large pool of target population is expected to propel growth in the region over the projected period. Moreover, the booming medical tourism industry is projected to attract global patients to this region. As a result, demand for medical gases and equipment is anticipated to increase significantly in Asia Pacific.
Growing M&A, investment in R&D, and product innovations are some of the strategies implemented by market players to sustain the competition and maintain their market share. For instance, in May 2014, Medical Gas Solution introduced the Medi Quick and Medi-1st kits to its product portfolio.
Major players in the global market include Air Liquide, Linde Gas, Air Products and Chemicals Inc., Matheson Tri-Gas Inc., and Praxair Inc. In 2013, the market was dominated by Air Liquide. Efficient distribution channel coupled with broad product portfolio enabled Linde Gas to capture market share of approximately 18%.
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Pharmacy automation involves automation and mechanization of tasks that include distribution and handling medication processes carried out in heath care centers and specialty pharmacy centers. The global pharmacy automation devices industry is projected to grow at a CAGR of 7.3% from 2014 to 2020 and reach over USD 8.99 billion.
Automation systems such as packaging and labeling systems, medication dispensing system, storage and retrieval systems, table-top counters and compounding systems are employed in order improve the efficacy of regular jobs within pharmacies. The market is expected to grow owing to features including system integration that increases productivity and time to clinicians for patient care, thereby lowering medication errors.
Rising demand for pharmaceutical products, progressively growing technology and demand for precise robotic equipment & tools to perform operations at a faster rate are expected to be the key factors for market growth. Untapped growth opportunities in countries such as Brazil, China, and India coupled with escalating demand for automation in pharmacy and healthcare operations is expected to drive growth over the forecast period.
The market was dominated by automated medication dispensing systems in 2013. It accounted for a share of over 47.8% owing to growing demand for accurate medication dispensing systems. Automated dispensing systems have the ability to reduce significantly error rates and the ability to dispense hands-free. They provide storage, recording of medication, distribution to resident care and computer controlled dispensation.
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Automated compounding systems are anticipated to grow rapidly at a CAGR of 8.4% from 2014 to 2020 owing to an increasing demand for mixing of medication and substantial decrease in total time to complete a dose.
The existence of IT healthcare systems and high rate of penetration in healthcare and pharmaceutical units resulted in North America occupying the largest regional market in 2013. It accounted for about 54.8% of the market revenue. Increasing healthcare overheads and R&D relevant to pharmacy automation devices are few factors responsible for its market share.
Asia Pacific is likely to grow at a CAGR of over 9.0% during the forecast period and is the most lucrative regional markets majorly due to improving healthcare infrastructure in emerging economies of China and India. Easy access available to new entrants including multinational pharmaceutical companies and distributors in this region coupled with the introduction of healthcare reforms in these countries is expected to drive market growth.
Key industry players include AmerisourceBergen Corporation, CareFusion Corporation, Accu-Chart Healthcare, ForHealth Technologies, GSE Scale Systems, Fulcrum Inc,McKesson Corporation, Innovation PharmaAssist Robotics, Pearson Medical Technologies, Health Robotics SRL, Kirby Lester, MedDispence, Pyxis Pharmacy Automation Systems, Medacist, MTS Medication Technologies, OmnicellInc, Cerner Corporation, Rice Lake Weighing Systems, Baxter International Inc., Aesynt Inc., ScriptPro LLC, Parat Systems Pharmacy Automation, Yuyama Co. Ltd, Swisslog Holding Ltd,Talyst Inc. and ScriptPro LLC.
Grand View Research has segmented the pharmacy automation devices market on the basis of application, end-use and region:
Pharmacy Automation Devices Application Outlook
• Automated Medication Dispensing Systems
• Automated Packaging And Labeling Systems
• Automated Storage And Retrieval Systems
• Automated Medication Compounding Systems
• Table Top Tablet Counters
Pharmacy Automation Devices End-use Outlook
• Hospital Pharmacy
• Retail Pharmacy
Pharmacy Automation Devices Regional Outlook
• North America
• Asia Pacific